Prior to this most recent Android v4.x update (aka ICS - Ice Cream Sandwich) on the Transformer TF101 - certain apps were reported to cause tablet mis-behavior, including lockups, reboots, and other negative user experiences.
Now that the update has been pushed out to many users of the original Transformer, and the number of problems appear to be drastically reduced...we should regroup regarding reports on apps still needing fixes.
It is important to note that certain apps still need updates to be ICS compatible. Often, the app release notes at the Android Market reflect ICS compatiblity if they have been updated.
Please post/report here if you have a specific app that continues to cause problems on your TF101 Transformer AFTER you have received/downloaded the latest ICS update that was pushed out starting 3/12/12.