There have been quite a few posts recently from member who have rooted their Transformers. The vast majority of those posts were because they had a problem related to rooting. Many of those problems were just that, problems.
Some of those who rooted found they couldn't get firmware updates. This may indicate that not enough research was done before rooting their device, mostly due to issues with later hardware versions of their Transformers.
It seems that some people feel that rooting is a must. Consider these points:
1. Ask yourself if there really is a good reason to root. Is there a must have app that won't install without a root?
2. Many have, in the past, determined they needed to root in order to backup, (Titanium Backup). I feel that ASUS wisely included an app that took care of that in order to reduce the possibility of rooting related problems.
3. Consider that the FW updates from ASUS have added value (AppBackup, SuperNote for example) that may reduce the need to root. I'm not even addressing custom ROMs. These value added apps and tweaks may have negated the original reason for the root so patience may pay off.
4. Consider ICS (nuff said)
5. Rooting has become a big part of the developers discussions but many of the posts are about a root that went wrong or messed with an update. I do feel for people who in some cases, at least temporarily, bricked their Transformers but keep that in mind
I'm not recommending for or against rooting here but you should really consider why you want to root, have a good reason, and do your due diligence research before jumping into a potential quick sand pit.
WHY? should be the first thing you ask.