1. I guess you are talking about your recent apps and the easiest way is to shut down and restart. You can go to settings - manage apps - and close each open app but that's kinda tedious
2. Facebook is currently not compatable but hopefully soon there are other apps as well as the website
3. my cloud I don't use but it is for your online storage of pictures, music, and videos
4. open the document and then choose save as and that will save it to the Transformer
5. Skype audio works but not video currently. The current work around is the onboard app called Talk and it is Google Talk.